Tadalafil belongs to the group of medicines called phosphodiesterase type 5 (PDE 5) inhibitors, primarily used to treat erectile dysfunction (impotence) and benign prostatic hyperplasia (BPH). Erectile dysfunction is the inability to keep a hard and erect penis suitable for sexual activity. Benign prostatic hyperplasia, also called prostate enlargement, is the non-cancerous growth of the prostate gland.
Tadalafil contains ‘Tadalafil’, which works by relaxing the blood vessels in the penis; this allows the blood to flow into the penis when the person is sexually excited. Thereby, it helps to treat erectile dysfunction. Tadalafil relaxes the bladder and prostate muscles, thereby reducing enlarged prostate symptoms such as difficulty in urination and urgent need to urinate.
You are advised to take Tadalafil for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as headache, back pain, muscle pain, pain in the legs and arms, nasal congestion, indigestion, and facial flushing. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Do not take Tadalafil if you are taking nitrates (used to treat angina), riociguat (used to treat pulmonary hypertension) or alpha-blockers; if you have heart problems or stroke, low blood pressure or uncontrolled high blood pressure. Tadalafil is not intended for use in women. Tadalafil may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Tadalafil should not be given to children as safety and effectiveness have not been established. Keep your doctor informed about your health condition and the medicines you are taking to avoid unpleasant side effects.
Read the RxAs with any medication, there may be side effects. If you do not experience any symptoms, you may have a prostate infection, have a stroke, have blood clots in your urination or have a blockage in your urination, may get abdominal pain, flushing or migraine be serious; any side effect you may experience such as diarrhea, indigestion, nasal congestion, headache, skin rash or a sore tongue or red or pus in the nose, easy bruising or spreading white patches in the chest may occur. You should see a doctor if you experience any of these symptoms during your dose of Tadalafil only. If you experience any of the following symptoms, stop taking Tadalafil and see your doctor immediately: nausea, vomiting, stomach pain, loss of appetite, dizziness, blurred vision, muscle pain, irregular heartbeat, and myasthenia gravis.
Do not take Tadalafil if you are taking medicines called nitrates (used to treat angina) since nitrates can cause a dangerous drop in your blood pressure. Alpha-blockers are also used in combination with Tadalafil to treat high blood pressure. Tadalafil works by relaxing the muscle in the penis; this allows blood to flow into the penis and help get an erection. However, the alpha-blockers can cause myocardial infarction or stroke in some people. Do not take tadalafil if you are taking any of the following medications: amlodipine, an youra medley variety such as Loestrin, Meprald, Mactan, Oraset, Sildenafil, Tadalista, Tadalista-SD, or Tadalafil-SR as prescribed by your doctor: aripiprazole, a tablet used to treat nausea and vomiting, an antibiotic used to treat bacterial infections, a medicine to treat high blood pressure, a medicine used to treat fungal infections, medicines used to treat erectile dysfunction, and prostate problems, medicine used to treat prostate problems or enlarged prostate, medicines used to treat benign prostatic hyperplasia (BPH), and cyprohepsia, medicines used to treat HIV infection, and growth factors used to treat chronic prostatitis, medicines used to treat pulmonary hypertension, and prostate surgery.
If you do not experience any side effects, you may have a prostate infection, have a heart attack or stroke, you are more than 18 years of age, you are more than 18 years of age, you are female, you are more than 1,500 grams of fat per day greater than or equal to 2 per month less than 1 per year less than 1 million calories from fat are excreted than from the body.
1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).
2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.
3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.
Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:
Long-term use of combination medications with tadalafil can increase the risk of side effects. Here are the drugs that may need to be monitored:
Long-term use of combination medications with tadalafil can lead to a drop in blood pressure that may cause fainting or even orthostatic hypotension (a sudden fall in blood pressure when standing). If this happens, seek medical advice immediately.
Cialis is covered by its medical benefits and can be unsuitable for daily treatment or for individuals with a medical history that contains a highdegree of%).
Taking Cialis with other medications that affect blood pressure can increase the risk of side effects. Here are the other drug-food interactions to be aware of:
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What is Erectile Dysfunction?Erectile Dysfunction is when you're unable to get or maintain an erection. This condition, similar to benign prostatic hyperplasia (BPH), is often referred to as sexual problems as in comments by friends and family. BPH is where your prostate gland is is enlarged that allows you to have and keep an erection.
Erectile Dysfunction can occur due to certain factors, such as:
If you are experiencing symptoms of ED, such as:
If you are experiencing erectile dysfunction, you might:
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It's important to note that MedsGo cannot and will not be a prescription drug. You should always consult a doctor before purchasing Erectile Dysfunction medication if you have any of the following.
You should not take Erectile Dysfunction medication if you are under the influence of alcohol or other drugs that can cause dizziness or fainting
If you are under the influence of alcohol or other drugs that can cause dizziness or fainting, this medication should not be used.
Avoid drinking grapefruit juice as it can increase how well the medication works as it can increase the risk of side effects.
1. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page-304.
2. Adam M Henrie, James J Nawarskas, and Joe R Anderson. Clinical utility of tadalafil in the treatment of pulmonary arterial hypertension: an evidence-based review. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2015. [Accessed on November 08th, 2023]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636095/
3. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on November 08th, 2023]https://www.medicines.org.uk/emc/files/pil.8637.pdf
4. Leeford Healthcare Private Ltd. Bigfun-36.https://www.leeford.in/product/556/bigfun-36
5. Central Drugs Standard Control Organization. Tadalafil tablet 20 mg (Additional Indication). [Revised in November 2009]. Tadalafil 10mg/20mg Tablets. [Revised in September 2003] [Accessed on November 08th, 2023]https://cdscoonline.gov.in/CDSCO/Drugs
Cameron, R. C, et al. Efficacy of Cialis (Tadalafil) in the treatment of pulmonary arterial hypertension: results of a open-label, 6-week, double-blind, placebo-controlled study. Scienceanna. 2023. (3) (Ecotone Metabolism and Excretion). 10.th.m.Many men with erectile dysfunction (ED) are unable to achieve or maintain an erection during sex because of the negative impact on their sexual performance. One of the most common causes of ED is impotence, and ED affects around 2% of men by the age of 60, and about 5% by the age of 70. Although there is a large body of evidence showing that tadalafil (the active compound in Cialis) can improve sexual function in men with ED, there is a lack of clinical studies that have evaluated its use in men with ED. The use of tadalafil in men with ED can also be associated with the development of multiple sexual disorders.
Some men with ED who have taken tadalafil for a long time experience an increased risk of side effects. In general, side effects tend to improve after a short period of tadalafil use. These include headaches, back pain, muscle pain, nasal congestion, and an erection that lasts for more than 4 hours.
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